Look out for these main research areas in our work:
Stem Cells

Immune genes are primed for robust transcription by proximal long noncoding rnas located in nuclear compartments

Fanucchi et al., Nature Genetics, 2019

Honey bee royalactin unlocks conserved pluripotency pathway in mammals

Fanucchi et al., Nature Communications, 2018

crispr-mediated reorganization of chromatin loop structure

Morgan et al., Journal of Vis Experiments, 2018

Epigenomics: technologies and applications

Wang and Chang, Circulation Research, 2018

Noncoding RNAs in Wound Healing: A New and Vast Frontier

Luan et al., Advances in Wound Care, 2018

Manipulation of nuclear architecture through CRISPR-mediated chromosomal looping

Morgan et al., Nature Communications, 2017

Transcription coactivator and lncRNA duet evoke Hox genes

Wang and Chang, PLoS Genetics, 2017

The Phenotypic Effects of Royal Jelly on Wild-Type D. melanogaster Are Strain-Specific

Morgan et al., PLoS Genetics, 2016

PICSAR: Long Noncoding RNA in Cutaneous Squamous Cell Carcinoma

Luo et al., Journal of Investigative Dermatology, 2016

RNA Sequencing for Identification of Differentially Expressed Noncoding Transcripts during Adipogenic Differentiation of Adipose-Derived Stromal Cells

Luan et al., Plastic and Reconstructive Surgery, 2015

Long noncoding RNA: significance and potential in skin biology

Wan and Wang, Cold Spring Harbor Perspectives in Medicine, 2014

Essential role of lncRNA binding for WDR5 maintenance of active chromatin and embryonic stem cell pluripotency

Yang et al., eLife, 2014

Molecular mechanisms of long noncoding RNAs

Wang and Chang, Molecular Cell, 2011

Crystal structure of the N-terminal region of human Ash2L shows a winged-helix motif involved in DNA binding

Chen et al., EMBO Reports, 2011

A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression

Wang et al., Nature, 2011